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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RANGAP1
All Species:
19.7
Human Site:
S574
Identified Species:
33.33
UniProt:
P46060
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P46060
NP_002874.1
587
63542
S574
N
S
A
L
E
S
C
S
F
A
R
H
S
L
L
Chimpanzee
Pan troglodytes
XP_001169198
587
63551
S574
N
S
A
L
E
S
C
S
F
A
R
H
S
L
L
Rhesus Macaque
Macaca mulatta
XP_001099367
1074
115836
R628
S
R
P
S
C
P
A
R
C
P
Q
A
C
I
C
Dog
Lupus familis
XP_538355
1323
142434
S574
N
G
A
L
E
S
C
S
F
A
R
H
S
L
L
Cat
Felis silvestris
Mouse
Mus musculus
P46061
589
63598
S576
N
G
A
L
E
T
C
S
F
A
R
H
N
L
L
Rat
Rattus norvegicus
NP_001012199
431
46388
G419
K
I
L
D
P
N
S
G
R
S
C
C
G
W
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509116
589
63641
P576
N
H
A
L
D
S
C
P
L
A
R
H
S
L
L
Chicken
Gallus gallus
NP_001006237
580
63057
S567
N
R
A
L
D
S
C
S
F
A
R
H
M
L
L
Frog
Xenopus laevis
O13066
580
62889
A567
N
G
V
L
E
N
N
A
S
A
R
H
T
L
L
Zebra Danio
Brachydanio rerio
NP_001070084
570
61996
S553
N
K
S
L
E
V
C
S
S
A
R
D
R
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VIW3
596
66051
K584
T
F
A
N
D
N
I
K
N
S
F
K
T
F
L
Honey Bee
Apis mellifera
XP_395378
580
63771
V559
I
R
I
S
K
K
K
V
M
D
S
L
Q
D
S
Nematode Worm
Caenorhab. elegans
P34342
960
105635
K871
S
A
P
L
K
S
C
K
M
S
E
P
A
L
Q
Sea Urchin
Strong. purpuratus
XP_001185909
387
41323
A375
K
Y
M
N
A
G
D
A
G
D
L
A
S
V
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
52.7
41.4
N.A.
88.6
66.6
N.A.
83.6
81.7
67.9
60.8
N.A.
32.3
43.6
25
40.7
Protein Similarity:
100
99.1
53.7
43
N.A.
95.5
70.6
N.A.
91.5
91.6
83.8
78
N.A.
53.1
59.9
38.2
54.8
P-Site Identity:
100
100
0
93.3
N.A.
80
0
N.A.
73.3
80
53.3
53.3
N.A.
13.3
0
26.6
6.6
P-Site Similarity:
100
100
20
93.3
N.A.
93.3
20
N.A.
80
86.6
73.3
60
N.A.
40
6.6
60
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
50
0
8
0
8
15
0
58
0
15
8
0
0
% A
% Cys:
0
0
0
0
8
0
58
0
8
0
8
8
8
0
8
% C
% Asp:
0
0
0
8
22
0
8
0
0
15
0
8
0
8
0
% D
% Glu:
0
0
0
0
43
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
8
0
0
0
0
0
0
36
0
8
0
0
8
0
% F
% Gly:
0
22
0
0
0
8
0
8
8
0
0
0
8
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
50
0
0
0
% H
% Ile:
8
8
8
0
0
0
8
0
0
0
0
0
0
8
0
% I
% Lys:
15
8
0
0
15
8
8
15
0
0
0
8
0
0
8
% K
% Leu:
0
0
8
65
0
0
0
0
8
0
8
8
0
65
58
% L
% Met:
0
0
8
0
0
0
0
0
15
0
0
0
8
0
8
% M
% Asn:
58
0
0
15
0
22
8
0
8
0
0
0
8
0
0
% N
% Pro:
0
0
15
0
8
8
0
8
0
8
0
8
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
8
0
8
0
8
% Q
% Arg:
0
22
0
0
0
0
0
8
8
0
58
0
8
0
0
% R
% Ser:
15
15
8
15
0
43
8
43
15
22
8
0
36
0
8
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
0
0
15
0
0
% T
% Val:
0
0
8
0
0
8
0
8
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _